Endocrine Abstracts

Background: Renal hyperparathyroidism (rHPT) may affect up to 30% of dialysispatients with end-stage renal disease (ESRD). rHPT is associated with an increased risk of cardiovascular events (CE) and bone diseases such as pain or renal osteodystrophy. Total or subtotal parathyroidectomy may be a chance to reduce the severity of the symptoms and decrease the risk of CE and death. Pre-operative scintigraphy and ultrasound diagnostics in rHPT may be insufficient at even up to 60% ...

Background: Carcinoid crisis (CC) may rarely occur as a complication of general anesthesia/surgery or peptide receptor radionuclide therapy (PRRT) in patients with neuroendocrine tumor (NET). The incidence of CC as a complication of PRRT is underestimated and comes to 10% of all radioisotope therapies. Progressive organ dysfunction, decrease or increase in blood pressure SBP <80 mmHg or >180 mmHg, unexplained tachyarrhythmia with heart rate >120/ min, bronchoconstr...

Introduction: The good expression of somatostatin receptors in neuroendocrine tumor tissue enables effective treatment with peptide receptor radionuclide therapy (PRRT). To date, there is no clear consensus on the optimal PRRT arrangement due to the possibility of the use of different radiopharmaceutical regimens. In theory, the simultaneous use of two radionuclides (90Y and 177Lu) with different energy and radiation ranges should be more effective than monotherapy. The main o...